Search results for "Diffusion of Innovation"
showing 10 items of 30 documents
Buccal drug delivery: what's new and what does the future hold?
2014
The buccal mucosa is the stratified squamous epithelial tissue inside lining of the cheeks. It is a favorable site of drug absorption since the tissue is non-keratinized, relatively immobile and strongly supplied with blood by a dense capillary-vessel network; moreover, it is highly tolerant to allergens, resistant to potentially harmful agents and has a relatively low enzymatic activity. The tissue consents quick onset of effect, offers an easily accessible and generally well-accepted site for drug delivery, is a useful route of administration in patients in an unconscious state (e.g., when swallowing is impaired), and is suitable for retentive dosage forms of administration. Buccal mucosa…
In vitro fertilization and andrology laboratory in 2030: expert visions.
2021
The aim of this article is to gather 9 thought leaders and their team members to present their ideas about the future of in vitro fertilization and the andrology laboratory. Although we have seen much progress and innovation in the laboratory over the years, there is still much to come, and this article looks at what these leaders think will be important in the future development of technology and processes in the laboratory.
Analysis of Production, Impact, and Scientific Collaboration on Difficult Airway Through the Web of Science and Scopus (1981-2013).
2017
Bibliometrics, the statistical analysis of written publications, is an increasingly popular approach to the assessment of scientific activity. Bibliometrics allows researchers to assess the impact of a field, or research area, and has been used to make decisions regarding research funding. Through bibliometric analysis, we hypothesized that a bibliometric analysis of difficult airway research would demonstrate a growth in authors and articles over time.Using the Web of Science (WoS) and Scopus databases, we conducted a search of published manuscripts on the difficult airway from January 1981 to December 2013. After removal of duplicates, we identified 2412 articles. We then analyzed the art…
Instrument transfer as knowledge transfer in neurophysiology: François Magendie's (1783-1855) early attempts to measure cerebrospinal fluid pressure.
2007
Francois Magendie's (1783-1855) experimental model for measuring blood pressure in animals, which he developed in 1838, had a major impact on French physiology in the nineteenth century, especially upon Etienne-Jules Marey (1830-1904) in Paris. In due course it was also adopted by other European investigators, such as the Leipzig physiologist Carl Ludwig (1816-1895), and by clinicians who developed it into a major measuring tool. Historians of science, however, have paid hardly any attention to Magendie's further laboratory investigations conducted with the assistance of Jean-Louis Marie Poiseuille's (1799-1869) sphygmometre (blood pressure meter). After having used the apparatus to conduct…
Factors in the global assimilation of collaborative information technologies: an exploratory investigation in five regions
2008
The diffusion of innovation theory is deployed to investigate the global assimilation of collaborative information technologies (CITs). Based on the concepts of IT acquisition and utilization, an assimilation framework is presented to highlight four states (limited, focused, lagging, and pervasive) that capture the assimilation of conferencing and groupware CITs. Data collected from 538 organizations in the United States, Australia, Hong Kong, Norway, and Switzerland are aggregated and analyzed to explore assimilation patterns and the influence of decision-making pattern, functional integration, promotion of collaboration, organization size, and IT function size on the assimilation of CITs.…
"Islands of Innovation" and "School-Wide Implementations" : Two Patterns of ICT-Based Pedagogical Innovations in Schools
2005
The study reported here is a secondary analysis of data collected in 10 schools as part of Israel’s participation in two international studies: IEA’s SITES Module 2, focusing on innovative pedagogical practices at the classroom level, and the OECD/CERI case studies of ICT and organizational innovation, focusing on ICT-related innovations at the school system level. We identify and analyze two patterns of ICT-based curricular innovations: “islands of innovation” and “school-wide implementations.” In the analysis of both patterns we focus on (a) the levels and domains of innovation reached in schools; (b) the communication agents and school variables affecting the diffusion of the innovation;…
Contours of diffusion of electronic data interchange in Finland
1998
Abstract Electronic Data Interchange (EDI)—despite its basic simplicity—forms a complex and inter-organizational innovation. This necessitates multiple points of observation and the use of multiple theoretical frames in accounting EDI diffusion processes. Based on field study data we deliver a multi-level account of EDI diffusion in Finland. The study clarifies how factors located on three levels of analysis can be applied to understand the unfolding of EDI adoption in different organizational constellations, here called diffusion patterns. We examine three families of diffusion patterns: local dyadic patterns; industry-wide networks; and national initiatives. Overall we discern five distin…
Effective digital collaboration in the construction industry – A case study of BIM deployment in a hospital construction project
2015
We examine a case of successful integrated BIM-based design in a construction project.We present a set of key factors influential to enable digital collaboration in this project.Key factors identified include: change agents, new roles, cloud computing, contracts, etc.We found integrated design to depend upon changing traditional work practices.The case is an example of BIM implementation and collaborative work in the AEC industry. Building information modeling (BIM) and related digital innovations can serve as a catalyst for more transparency, tighter integration, and increased productivity in the architecture, engineering, and construction industry. Yet, many project teams struggle with ho…
Validation of the group nuclear safety climate questionnaire.
2013
Abstract Introduction Group safety climate is a leading indicator of safety performance in high reliability organizations. Zohar and Luria (2005) developed a Group Safety Climate scale (ZGSC) and found it to have a single factor. Method The ZGSC scale was used as a basis in this study with the researchers rewording almost half of the items on this scale, changing the referents from the leader to the group, and trying to validate a two-factor scale. The sample was composed of 566 employees in 50 groups from a Spanish nuclear power plant. Item analysis, reliability, correlations, aggregation indexes and CFA were performed. Results Results revealed that the construct was shared by each unit, a…
Uterus Transplantation
2018
Uterus transplantation (UTx) has been successfully introduced as a treatment option for women with absolute uterine factor infertility (AUFI). AUFI representing approximately 3% to 5% of the female general population is linked to either congenital uterine agenesis (Mayer-Rokitansky-Küster-Hauser syndrome), major congenital uterine malformation (hypoplastic uterus, fraction of bicornuate/unicornuate uterus), a surgically absent uterus, or an acquired condition (intrauterine adhesions, leiomyoma) linked to uterine malfunction that causes implantation failure or defect placentation. The world's first clinical uterus transplant was performed in 2000. However, a hysterectomy became necessary sho…